Do statins decrease the production of ketones?

By Dr. Stephen Phinney and the Virta Team

Statins are a class of drugs that target the body’s production of cholesterol in the liver, but they have other effects as well. One of these side effects is a reduction in the body’s level of inflammation, which may be beneficial. There are no known problems associated with combining statin use with a well-formulated ketogenic diet. In fact, Jeff Volek’s team did a study in which they recruited people who were already taking a statin and then put them on a ketogenic diet for 6 weeks. As a group, they lost weight and had improved blood lipids (e.g., reduced triglycerides, reduced small LDL particles). But to the point of this question, their blood ketone levels went up into the nutritional ketosis range as expected.

Citations:

Dietary carbohydrate restriction improves insulin sensitivity, blood pressure, microvascular function, and cellular adhesion markers in individuals taking statins.
Ballard KD, Quann EE, Kupchak BR, Volk BM, Kawiecki DM, Fernandez ML, Seip RL, Maresh CM, Kraemer WJ, Volek JS.
Nutr Res. 2013 Nov;33(11):905-12.

Back to Keto FAQ


Related blog posts

Dr. Stephen Phinney on Nutritional Ketosis and Ketogenic Diets: Video Series - Dr. Stephen Phinney put together a three-part video series on ketogenic diets and nutritional ketosis. You'll learn the nutrition science… ... Read More
Ketone Supplements: The Pros and Cons - Ketone supplements rapidly and transiently increase blood concentrations of BOHB. On the surface, this seems like it should promote positive… ... Read More
Sarah Hallberg, DO, MS Reversing Diabetes 101 with Dr. Sarah Hallberg: The Truth About Carbs, Blood Sugar and Reversing Type 2 Diabetes - You may have heard a lot about type 2 diabetes, but do you know what it actually does to your… ... Read More

Leave a reply

Your email address will not be published.